Agarose Gel Electrophoresis na RNA

Wani sabon bincike daga RNA

Kwanan nan, bincike ya gano cewa bambance-bambancen kwayoyin halittawanda ke rage matakan gyare-gyare na RNA guda biyu suna da alaƙa da autoimmune da yanayin tsaka-tsaki na rigakafi.

Kwayoyin RNA na iya yin gyare-gyare. Misali, ana iya saka nucleotides, share, ko canza su. Ɗaya daga cikin gyare-gyaren da aka fi sani da shi, wanda sabon bincike ya nuna yana taka muhimmiyar rawa a farkon cutar kumburi, shine canza adenosine na nucleotide zuwa inosine a cikin RNA guda biyu. Nazarinya kasanceaka bugaon Agusta 3 a cikin Halitta ya nuna cewa bambance-bambancen kwayoyin halitta waɗanda ke lalata wannan ƙayyadaddun gyare-gyare suna da alaƙa da haɓakar haɓakar ƙwayoyin cuta da ƙwayoyin cuta kamar su psoriasis, cututtukan hanji mai kumburi, da nau'in ciwon sukari na 1. Marubutan sun ba da shawarar cewa furotin na firikwensin yana iya yin kuskuren waɗannan RNA waɗanda ba a gyara su ba don ƙwayoyin waje, yana haifar da amsa mai kumburi.

Masanin ilimin kwayoyin halitta yayi tunanin cewa's ainihin babban ci gaba ne, kuma an same shiyana da "mafi ban mamaki" yadda mahimmancin gyaran RNA ya bayyana ga cututtuka masu kumburi, idan aka kwatanta da maganganun kwayoyin halitta ko splicing.

Gaskiya ne mai girma bincike. Kuma a matsayin tallace-tallace na samfuran electrophoresis, Ina sha'awar menene RNA, kuma ta yaya masana kimiyya ke nazarin RNA ta hanyar electrophoresis? Yana da ƙwararriyar gaske kuma ilimi ne a gare ni amma har yanzu yana da daɗi don bincika shi.

Menene RNA?

RNA, gajere don Ribonucleic acid, acid nucleic da ke cikin dukkan sel masu rai. Ba kamar DNA ba, RNA shine mafi yawan lokuta mai ɗauri ɗaya. Babban aikinsa shi ne yin aiki a matsayin manzo mai ɗauke da umarni daga DNA don sarrafa haɗin sunadarai, kodayake a wasu ƙwayoyin cuta RNA maimakon DNA na ɗauke da bayanan kwayoyin halitta.

Agarose Gel Electrophoresis na RNA

Mutane na iyatantance ingancin RNA ta gel electrophoresis.

Abubuwan da aka bayar na Beijing Liuyi Biotechnology Co.,Ltdƙwararrun masana'anta da ke mai da hankali kan samfuran electrophoresis sama da shekaru 50, suna ba da tankunan tankuna na electrophoresis (ɗakuna / sel) don gel electrophoresis, kamar tankunan electrophoresis na kwance (ɗakuna / sel) don gel electrophoresis na agarose, da tankuna na lantarki na tsaye (ɗakuna / sel) don gina jiki gel electrophoresis. A halin yanzu, yana kuma samar da nau'ikan wutar lantarki na lantarki daban-daban, mai duba akwatin duhu mai duhu da UV transilluminator. Kuna iya zaɓar Liuyi na Beijing's electrophoresis tankuna (ɗakuna/kwayoyin) don auna nauyin kwayoyin halitta na RNA da kuma raba RNA masu girma dabam don dakin binciken ku.

Anan za mu gabatar da nau'in tankin lantarki na kwance (jama'a / tantanin halitta) samfurin DYCP-31DN daga samfuran samfuran mu na 31.

DYCP-31DN ƙaramin tanki ne a kwance a kwance (ɗaki/cell) don auna nauyin kwayoyin RNA ko DNA da raba su.